St. Louis, Missouri: A Guide to the Best New Hotels in the Gateway City
St. Louis, Missouri, is a city that effortlessly blends historic charm with modern innovation. Known for its iconic Gateway Arch, vibrant neighborhoods, and rich cultural scene, St. Louis is a destination that appeals to travelers of all kinds. With a mix of new openings and established favorites, the city’s hotel scene is thriving. Let’s explore some of the best new hotels St. Louis has to offer.
1. SpringHill Suites St. Louis Chesterfield (Opening June 2025)
Marriott | Affordable and Convenient
Hotel Features:
The SpringHill Suites St. Louis Chesterfield, opening in June 2025, will offer comfortable rooms, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in Chesterfield, this hotel will be close to popular attractions like the Chesterfield Mall and the Butterfly House.
Why Stay Here?
For a budget-friendly stay with great amenities, the SpringHill Suites St. Louis Chesterfield is a solid choice.
2. Hampton Inn by Hilton St Louis Airport (Opening May 2025)
Hilton | Affordable and Reliable
Hotel Features:
The Hampton Inn by Hilton St Louis Airport, opening in May 2025, will offer comfortable rooms, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located near St. Louis Lambert International Airport, this hotel will be perfect for travelers with early flights or layovers. It’s also a short drive from downtown St. Louis.
Why Stay Here?
For a budget-friendly stay with great amenities, the Hampton Inn by Hilton St Louis Airport is a solid choice.
3. AC Hotel St. Louis Clayton (Opening November 2024)
Marriott | Upscale Comfort
Hotel Features:
The AC Hotel St. Louis Clayton, opening in November 2024, will offer luxurious rooms, a rooftop pool, a fitness center, and an on-site restaurant serving locally inspired cuisine.
Location Benefits:
Located in Clayton, this hotel will be close to popular attractions like the St. Louis Art Museum and Forest Park.
Why Stay Here?
For an upscale and comfortable stay, the AC Hotel St. Louis Clayton is a must-visit.
4. 21c Museum Hotel St. Louis (Opened August 2023)
N/A | Boutique Luxury
Hotel Features:
The 21c Museum Hotel St. Louis offers stylish rooms, a rooftop pool, a fitness center, and an on-site restaurant serving locally inspired cuisine.
Location Benefits:
Located in downtown St. Louis, this hotel is close to popular attractions like the Gateway Arch, the City Museum, and the St. Louis Union Station.
Why Stay Here?
For a boutique luxury experience, the 21c Museum Hotel St. Louis is a top choice.
5. Residence Inn St. Louis Clayton (Opened March 2023)
Marriott | Extended Stay Comfort
Hotel Features:
The Residence Inn St. Louis Clayton offers spacious suites with fully equipped kitchens, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in Clayton, this hotel is close to popular attractions like the St. Louis Art Museum and Forest Park.
Why Stay Here?
For a comfortable and convenient extended stay, the Residence Inn St. Louis Clayton is a great option.
6. Tru by Hilton St Louis Downtown (Opened May 2022)
Hilton | Affordable and Modern
Hotel Features:
The Tru by Hilton St Louis Downtown offers modern, no-frills rooms, complimentary breakfast, and a fitness center.
Location Benefits:
Located in downtown St. Louis, this hotel is close to popular attractions like the Gateway Arch, the City Museum, and the St. Louis Union Station.
Why Stay Here?
For a budget-friendly stay with great amenities, the Tru by Hilton St Louis Downtown is a solid choice.
7. AC Hotel St. Louis Chesterfield (Opened April 2022)
Marriott | Upscale Comfort
Hotel Features:
The AC Hotel St. Louis Chesterfield offers luxurious rooms, a rooftop pool, a fitness center, and an on-site restaurant serving locally inspired cuisine.
Location Benefits:
Located in Chesterfield, this hotel is close to popular attractions like the Chesterfield Mall and the Butterfly House.
Why Stay Here?
For an upscale and comfortable stay, the AC Hotel St. Louis Chesterfield is a must-visit.
8. AC Hotel St Louis Central West End (Opened December 2021)
Marriott | Upscale Comfort
Hotel Features:
The AC Hotel St Louis Central West End offers luxurious rooms, a rooftop pool, a fitness center, and an on-site restaurant serving locally inspired cuisine.
Location Benefits:
Located in the Central West End, this hotel is close to popular attractions like Forest Park, the St. Louis Art Museum, and the Missouri Botanical Garden.
Why Stay Here?
For an upscale and comfortable stay, the AC Hotel St Louis Central West End is a must-visit.
9. TownePlace Suites Brentwood (Opened October 2021)
Marriott | Extended Stay Comfort
Hotel Features:
The TownePlace Suites Brentwood offers spacious suites with fully equipped kitchens, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in Brentwood, this hotel is close to popular attractions like the Galleria Mall and the Magic House.
Why Stay Here?
For a comfortable and convenient extended stay, the TownePlace Suites Brentwood is a great option.
10. Comfort Suites, St. Louis (Opened September 2021)
N/A | Affordable and Convenient
Hotel Features:
The Comfort Suites, St. Louis offers comfortable rooms, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in downtown St. Louis, this hotel is close to popular attractions like the Gateway Arch, the City Museum, and the St. Louis Union Station.
Why Stay Here?
For a budget-friendly stay with great amenities, the Comfort Suites, St. Louis is a solid choice.
11. Holiday Inn St. Louis – Creve Coeur (Opened December 2020)
IHG | Affordable and Convenient
Hotel Features:
The Holiday Inn St. Louis – Creve Coeur offers comfortable rooms, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in Creve Coeur, this hotel is close to popular attractions like Creve Coeur Lake Memorial Park and the St. Louis Galleria.
Why Stay Here?
For a budget-friendly stay with great amenities, the Holiday Inn St. Louis – Creve Coeur is a solid choice.
12. Fairfield Inn & Suites St Louis South (Opened November 2020)
Marriott | Affordable and Convenient
Hotel Features:
The Fairfield Inn & Suites St Louis South offers comfortable rooms, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in South St. Louis, this hotel is close to popular attractions like the Missouri Botanical Garden and the Anheuser-Busch Brewery.
Why Stay Here?
For a budget-friendly stay with great amenities, the Fairfield Inn & Suites St Louis South is a solid choice.
13. Element St. Louis Midtown (Opened September 2020)
Marriott | Eco-Friendly Comfort
Hotel Features:
The Element St. Louis Midtown offers eco-friendly rooms with modern amenities, complimentary breakfast, a fitness center, and an outdoor pool.
Location Benefits:
Located in Midtown, this hotel is close to popular attractions like the Fox Theatre and the St. Louis University campus.
Why Stay Here?
For an eco-conscious stay in a prime location, the Element St. Louis Midtown is a great choice.
14. Aloft St. Louis Cortex (Opened June 2020)
Marriott | Trendy and Vibrant
Hotel Features:
The Aloft St. Louis Cortex offers trendy, compact rooms, a rooftop bar, a fitness center, and an on-site restaurant serving tapas-style dishes.
Location Benefits:
Located in the Cortex Innovation Community, this hotel is close to popular attractions like Forest Park and the St. Louis Art Museum.
Why Stay Here?
For a stylish and modern stay, the Aloft St. Louis Cortex is a top pick.
15. Fairfield Inn & Suites by Marriott St. Louis Downtown (Opened February 2020)
Marriott | Affordable and Convenient
Hotel Features:
The Fairfield Inn & Suites by Marriott St. Louis Downtown offers comfortable rooms, complimentary breakfast, an outdoor pool, and a fitness center.
Location Benefits:
Located in downtown St. Louis, this hotel is close to popular attractions like the Gateway Arch, the City Museum, and the St. Louis Union Station.
Why Stay Here?
For a budget-friendly stay with great amenities, the Fairfield Inn & Suites by Marriott St. Louis Downtown is a solid choice.
16. Hotel Indigo St. Louis – Downtown (Opened November 2019)
IHG | Boutique Charm
Hotel Features:
The Hotel Indigo St. Louis – Downtown offers stylish rooms, a rooftop pool, a fitness center, and an on-site restaurant serving locally inspired cuisine.
Location Benefits:
Located in downtown St. Louis, this hotel is close to popular attractions like the Gateway Arch, the City Museum, and the St. Louis Union Station.
Why Stay Here?
For a boutique and charming stay, the Hotel Indigo St. Louis – Downtown is a top choice.
Final Thoughts
St. Louis’ hotel scene offers a mix of historic charm, modern comforts, and budget-friendly options. Whether you’re here for the Gateway Arch, the museums, or the vibrant neighborhoods, these hotels provide the perfect home base for your adventures. Book your stay today and experience the best of St. Louis!
Which of these hotels are you most excited to visit? Let us know in the comments below!
Note: Be sure to check each hotel’s website for the latest updates, availability, and pricing.
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